pepteed
Research4 min readUpdated May 2026

Melanotan-1 (afamelanotide): a research overview

Melanotan-1, also called afamelanotide, is a peptide studied in melanocortin and pigmentation research. This overview covers its structure and handling, with no therapeutic or dosing claims.

What it is

Melanotan-1 is a linear analogue of alpha-melanocyte-stimulating hormone (α-MSH). It differs structurally from the cyclic Melanotan-2, and the two are commonly compared in melanocortin research.

Why it is studied

Melanotan-1 appears in preclinical and in-vitro pigmentation and melanocortin literature as a research tool. The conclusions belong to those studies; this page makes no claim about human effects.

Handling notes

  • Supplied lyophilised; reconstitute gently.
  • Keep the dry solid sealed, cold and dark.
  • Refrigerate after reconstitution and aliquot for repeated use.

For in-vitro research use only. Not for human or veterinary use.

Mentioned in the catalog
For in-vitro research use only. This guide covers general laboratory handling and is not medical, clinical or dosing advice.